Optimizing mycobacteria molecular diagnostics: No decontamination! Human DNA depletion? Greener storage at 4 °C!

IntroductionTuberculosis (TB) is an infectious disease caused by the group of bacterial pathogens Mycobacterium tuberculosis complex (MTBC) and is one of the leading causes of death worldwide. Timely diagnosis and treatment of drug-resistant TB is a key pillar of WHO’s strategy to combat global TB....

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Prajwal Prajwal, Turlough Neary, Katja Rohrbach, Pascal Bittel, Pauline C. Göller, Thorsten Buch, Sebastian Dümcke, Peter M. Keller
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-04-01
Subjects:	sputum decontamination NALC-NaOH saponin human DNA depletion molecular diagnostics mycobacteria
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1104752/full