Clonal hematopoiesis and atherosclerosis

Clonal hematopoiesis of indeterminate potential (CHIP) has emerged as a previously unrecognized, potent, age-related, and common risk factor for atherosclerosis. Somatic mutations in certain known leukemia driver genes give rise to clones of mutant cells in peripheral blood. The increased risk of de...

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Bibliographic Details
Published in:The Journal of Clinical Investigation
Main Authors: Ohad Oren, Aeron M. Small, Peter Libby
Format: Article
Language:English
Published: American Society for Clinical Investigation 2024-10-01
Online Access:https://doi.org/10.1172/JCI180066