ENOblock Does Not Inhibit the Activity of the Glycolytic Enzyme Enolase.

Inhibition of glycolysis is of great potential for the treatment of cancer. However, inhibitors of glycolytic enzymes with favorable pharmacological profiles have not been forthcoming. Due to the nature of their active sites, most high-affinity transition-state analogue inhibitors of glycolysis enzy...

Full description

Bibliographic Details
Published in:PLoS ONE
Main Authors: Nikunj Satani, Yu-Hsi Lin, Naima Hammoudi, Sudhir Raghavan, Dimitra K Georgiou, Florian L Muller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Online Access:http://europepmc.org/articles/PMC5193436?pdf=render