Engineering of dendritic cell bispecific extracellular vesicles for tumor-targeting immunotherapy

Summary: Advances in the development of therapeutic extracellular vesicles (EVs) for cancer immunotherapy have allowed them to emerge as an alternative to cell therapy. In this proof-of-concept work, we develop bispecific EVs (BsEVs) by genetically engineering EV-producing dendritic cells (DCs) with...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Fang Xu, Dongpeng Jiang, Jialu Xu, Huaxing Dai, Qin Fan, Ziying Fei, Beilei Wang, Yue Zhang, Qingle Ma, Qianyu Yang, Yitong Chen, Edikan A. Ogunnaike, Jianhong Chu, Chao Wang
Format:	Article
Language:	English
Published:	Elsevier 2023-10-01
Subjects:	CP: Immunology CP: Cancer
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124723011506