Boldine modulates glial transcription and functional recovery in a murine model of contusion spinal cord injury

Membrane channels such as those formed by connexins (Cx) and P2X7 receptors (P2X7R) are permeable to calcium ions and other small molecules such as adenosine triphosphate (ATP) and glutamate. Release of ATP and glutamate through these channels is a key mechanism driving tissue response to traumas su...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Carlos A. Toro, Kaitlin Johnson, Jens Hansen, Mustafa M. Siddiq, Walter Vásquez, Wei Zhao, Zachary A. Graham, Juan C. Sáez, Ravi Iyengar, Christopher P. Cardozo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Subjects:	boldine contusion SCI functional recovery hemichannel blockade spared white matter glial response
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2023.1163436/full