Real-time imaging of cGMP signaling shows pronounced differences between glomerular endothelial cells and podocytes

Abstract Recent clinical trials of drugs enhancing cyclic guanosine monophosphate (cGMP) signaling for cardiovascular diseases have renewed interest in cGMP biology within the kidney. However, the role of cGMP signaling in glomerular endothelial cells (GECs) and podocytes remains largely unexplored....

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Nelli Rutkowski, Frederik Görlitz, Eva Wiesner, Julia Binz-Lotter, Susanne Feil, Robert Feil, Thomas Benzing, Matthias J. Hackl
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-10-01
Subjects:	cGMP signaling sGC pGC Podocyte Glomerular endothelial cell GECs
Online Access:	https://doi.org/10.1038/s41598-024-76768-1