ID proteins promote the survival and primed-to-naive transition of human embryonic stem cells through TCF3-mediated transcription

Abstract Inhibition of DNA binding proteins 1 and 3 (ID1 and ID3) are important downstream targets of BMP signalling that are necessary for embryonic development. However, their specific roles in regulating the pluripotency of human embryonic stem cells (hESCs) remain unclear. Here, we examined the...

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Bibliographic Details

Published in:	Cell Death and Disease
Main Authors:	Haibin Jiang, Mingxia Du, Yaning Li, Tengfei Zhou, Jia Lei, Hongqing Liang, Zhen Zhong, Rafia S. Al-Lamki, Ming Jiang, Jun Yang
Format:	Article
Language:	English
Published:	Nature Publishing Group 2022-06-01
Online Access:	https://doi.org/10.1038/s41419-022-04958-8