Efficacy and safety of single-pill amlodipine/losartan versus losartan in patients with inadequately controlled hypertension after losartan treatment: a multicenter, double-blind, randomized phase III clinical trial

ObjectiveSingle-pill amlodipine besylate (AML) plus losartan (LOS) has been used to treat inadequately controlled hypertension after antihypertensive monotherapy; however, relevant data in China are limited. This study aimed to compare the efficacy and safety of single-pill AML/LOS and LOS alone in...

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Bibliographic Details

Published in:	Frontiers in Cardiovascular Medicine
Main Authors:	Shuyang Zhang, Ying Li, Xin Xu, Rui Xu, Linchao Zhang, Xiaoqun Wan, Zhuhua Yao, Yuemin Sun, Yong Liu, Jianping Bin, Zhen Wang, Shuren Li, Ping Yang, Xiping Xu, Weidong Liang, Xiaohong Gao, Xiaodong Li, Min Jia, Guang Ma, Xiang Gu, Chang Hong
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Subjects:	amlodipine besylate losartan inadequately controlled hypertension blood pressure safety
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2023.1177166/full