Age-specific signatures of glioblastoma at the genomic, genetic, and epigenetic levels.

Age is a powerful predictor of survival in glioblastoma multiforme (GBM) yet the biological basis for the difference in clinical outcome is mostly unknown. Discovering genes and pathways that would explain age-specific survival difference could generate opportunities for novel therapeutics for GBM....

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Serdar Bozdag, Aiguo Li, Gregory Riddick, Yuri Kotliarov, Mehmet Baysan, Fabio M Iwamoto, Margaret C Cam, Svetlana Kotliarova, Howard A Fine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Online Access:http://europepmc.org/articles/PMC3639162?pdf=render