Solid-Phase Synthesized Copolymers for the Assembly of pH-Sensitive Micelles Suitable for Drug Delivery Applications

Diblock copolymers of polyhistidine are known for their self-assembly into micelles and their pH-dependent disassembly due to the amphiphilic character of the copolymer and the unsaturated imidazole groups that undergo a hydrophobic-to-hydrophilic transition in an acidic pH. This property has been l...

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Bibliographic Details

Published in:	Nanomaterials
Main Authors:	Razvan Ghiarasim, Crina Elena Tiron, Adrian Tiron, Mihail-Gabriel Dimofte, Mariana Pinteala, Alexandru Rotaru
Format:	Article
Language:	English
Published:	MDPI AG 2022-05-01
Subjects:	polyhistidine copolymers micelles doxorubicin tumor cells release studies
Online Access:	https://www.mdpi.com/2079-4991/12/11/1798