Neuronal repair after spinal cord injury by in vivo astrocyte reprogramming mediated by the overexpression of NeuroD1 and Neurogenin-2

Abstract Background As a common disabling disease, irreversible neuronal death due to spinal cord injury (SCI) is the root cause of functional impairment; however, the capacity for neuronal regeneration in the developing spinal cord tissue is limited. Therefore, there is an urgent need to investigat...

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Bibliographic Details

Published in:	Biological Research
Main Authors:	Zuliyaer Talifu, Chunjia Zhang, Xin Xu, Yunzhu Pan, Han Ke, Zehui Li, Wubo Liu, Huayong Du, Xiaoxin Wang, Feng Gao, Degang Yang, Yingli Jing, Yan Yu, Liangjie Du, Jianjun Li
Format:	Article
Language:	English
Published:	BMC 2024-08-01
Subjects:	Spinal cord injury Astrocytes Reprogramming Nerve regeneration Nerve repair
Online Access:	https://doi.org/10.1186/s40659-024-00534-w