Nutritional control of body size through FoxO-Ultraspiracle mediated ecdysone biosynthesis

Despite their fundamental importance for body size regulation, the mechanisms that stop growth are poorly understood. In Drosophila melanogaster, growth ceases in response to a peak of the molting hormone ecdysone that coincides with a nutrition-dependent checkpoint, critical weight. Previous studie...

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Bibliographic Details

Published in:	eLife
Main Authors:	Takashi Koyama, Marisa A Rodrigues, Alekos Athanasiadis, Alexander W Shingleton, Christen K Mirth
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2014-11-01
Subjects:	ecdysone nutrition-dependent signaling insulin/insulin-like growth factor target of rapamycin critical weight body size
Online Access:	https://elifesciences.org/articles/03091