In silico and multi-spectroscopic analyses on the interaction of 5-amino-8-hydroxyquinoline and bovine serum albumin as a potential anticancer agent

Abstract 5-Amino-8-hydroxyquinoline (5A8HQ), an amino derivative of 8-hydroxyquinoline, has become a potential anticancer candidate because of its promising proteasome inhibitory activity to overcome and yet synergize bortezomib for fighting cancers. Therefore, in this study, its physicochemical pro...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Waralee Ruankham, Kamonrat Phopin, Ratchanok Pingaew, Supaluk Prachayasittikul, Virapong Prachayasittikul, Tanawut Tantimongcolwat
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Online Access:https://doi.org/10.1038/s41598-021-99690-2