In-Depth Characterization of Endo-Lysosomal Aβ in Intact Neurons

Amyloid-beta (Aβ) peptides are produced within neurons. Some peptides are released into the brain parenchyma, while others are retained inside the neurons. However, the detection of intracellular Aβ remains a challenge since antibodies against Aβ capture Aβ and its precursor proteins (i.e., APP and...

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发表在:	Biosensors
Main Authors:	Alec K. McKendell, Mei C. Q. Houser, Shane P. C. Mitchell, Michael S. Wolfe, Oksana Berezovska, Masato Maesako
格式:	文件
语言:	英语
出版:	MDPI AG 2022-08-01
主题:	Alzheimer’s disease fluorescence resonance energy transfer (FRET) γ-secretase glycoconjugates intracellular amyloid-beta (Aβ) lysosomes
在线阅读:	https://www.mdpi.com/2079-6374/12/8/663