Impaired liver regeneration and lipid homeostasis in CCl4 treated WDR13 deficient mice

Abstract WDR13 - a WD repeat protein, is abundant in pancreas, liver, ovary and testis. Absence of this protein in mice has been seen to be associated with pancreatic β-cell proliferation, hyperinsulinemia and age dependent mild obesity. Previously, we have reported that the absence of WDR13 in diab...

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Bibliographic Details

Published in:	Laboratory Animal Research
Main Authors:	Arun Prakash Mishra, Archana B. Siva, Chandrashekaran Gurunathan, Y. Komala, B. Jyothi Lakshmi
Format:	Article
Language:	English
Published:	BMC 2020-11-01
Subjects:	Fatty liver PPARg Hepatosteatosis Hypertriglyceridemia Hepatotoxin
Online Access:	http://link.springer.com/article/10.1186/s42826-020-00076-8