Antigenic Peptide Prediction From E6 and E7 Oncoproteins of HPV Types 16 and 18 for Therapeutic Vaccine Design Using Immunoinformatics and MD Simulation Analysis

Human papillomavirus (HPV) induced cervical cancer is the second most common cause of death, after breast cancer, in females. Three prophylactic vaccines by Merck Sharp & Dohme (MSD) and GlaxoSmithKline (GSK) have been confirmed to prevent high-risk HPV strains but these vaccines have been s...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Basit Jabbar, Shazia Rafique, Outi M. H. Salo-Ahen, Amjad Ali, Mobeen Munir, Muhammad Idrees, Muhammad Usman Mirza, Michiel Vanmeert, Syed Zawar Shah, Iqra Jabbar, Muhammad Adeel Rana
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-12-01
Subjects:	binding affinity computational epitope prediction docking peptide vaccine human papillomavirus
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2018.03000/full