Real-time monitoring of cAMP in brown adipocytes reveals differential compartmentation of β1 and β3-adrenoceptor signalling

Objective: 3′,5′-Cyclic adenosine monophosphate (cAMP) is a central second messenger governing brown adipocyte differentiation and function. β-adrenergic receptors (β-ARs) stimulate adenylate cyclases which produce cAMP. Moreover, cyclic nucleotide levels are tightly controlled by phosphodiesterases...

Full description

Bibliographic Details

Published in:	Molecular Metabolism
Main Authors:	Sukanya Arcot Kannabiran, Dominic Gosejacob, Birte Niemann, Viacheslav O. Nikolaev, Alexander Pfeifer
Format:	Article
Language:	English
Published:	Elsevier 2020-07-01
Subjects:	Brown adipocytes cAMP PDE FRET Beta receptors Compartmentation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2212877820300600