JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage

Cypermethrin (CYP), a widely-used composite pyrethroid pesticide, has underlying nephrotoxic effects. To elucidate potential roles of the MAPK pathway, the Jag/Notch pathway, and miRNAs in CYP-mediated kidney lesion, Sprague-Dawley rats and glomerular mesangial cells were used in this work. Results...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Ecotoxicology and Environmental Safety
المؤلفون الرئيسيون:	Changjiang Liu, Mingzhu Wu, Jiayuan Qu, Xu Huang, Qiang Zeng, Mei Ha
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Elsevier 2022-06-01
الموضوعات:	Kidney damage CXCL16 JNK/c-Jun pathway Jag1/Notch2/Hes1 pathway Cypermethrin
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S0147651322004225