Old Drug, New Trick: Tilorone, a Broad-Spectrum Antiviral Drug as a Potential Anti-Fibrotic Therapeutic for the Diseased Heart

Cardiac fibrosis is associated with most forms of cardiovascular disease. No reliable therapies targeting cardiac fibrosis are available, thus identifying novel drugs that can resolve or prevent fibrosis is needed. Tilorone, an antiviral agent, can prevent fibrosis in a mouse model of lung disease....

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書誌詳細

出版年:	Pharmaceuticals
主要な著者:	Duncan Horlock, David M. Kaye, Catherine E. Winbanks, Xiao-Ming Gao, Helen Kiriazis, Daniel G. Donner, Paul Gregorevic, Julie R. McMullen, Bianca C. Bernardo
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2021-03-01
主題:	heart failure fibrosis tilorone pressure overload fibroblast treatment
オンライン･アクセス:	https://www.mdpi.com/1424-8247/14/3/263