TNF signaling maintains local restriction of bacterial founder populations in intestinal and systemic sites during oral Yersinia infection

ABSTRACT Enteroinvasive bacterial pathogens are responsible for an enormous worldwide disease burden that critically affects the young and immunocompromised. Yersinia pseudotuberculosis is a gram-negative enteric pathogen closely related to the plague agent Y. pestis that colonizes intestinal tissue...

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Bibliographic Details

Published in:	mBio
Main Authors:	Stefan T. Peterson, Katherine G. Dailey, Karthik Hullahalli, Daniel Sorobetea, Rina Matsuda, Jaydeen Sewell, Winslow Yost, Rosemary O'Neill, Suhas Bobba, Nicolai Apenes, Matthew E. Sherman, George I. Balazs, Charles-Antoine Assenmacher, Arin Cox, Matthew Lanza, Sunny Shin, Matthew K. Waldor, Igor E. Brodsky
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-10-01
Subjects:	Yersinia infectious disease tumor necrosis factor gastrointestinal infection infection dynamics bacterial infection
Online Access:	https://journals.asm.org/doi/10.1128/mbio.01779-25