Proteogenomic characterization of invasive breast tumors in young women

Abstract Breast cancer in women <40, accounting for ~5% of all breast cancer cases diagnosed in the U.S., is more aggressive and associated with worse outcomes compared to breast cancer in older women. We performed a first-ever integrated proteogenomic study from a matched cohort of laser-microdi...

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Bibliographic Details
Published in:npj Breast Cancer
Main Authors: Praveen-Kumar Raj-Kumar, Jianfang Liu, Anthony R. Soltis, Nicholas W. Bateman, Qingrong Chen, Lori A. Sturtz, Brenda Deyarmin, Mariaelena Pierobon, Tamara A. Abulez, Anupama Praveen-Kumar, Xijun Zhang, Trinh Nguyen, Chunhua Yan, Ying Hu, Kate Guion, Jeffrey A. Hooke, Albert J. Kovatich, Leigh Fantacone-Campbell, Brad Mostoller, Leonid Kvecher, Stella Somiari, Patricia S. Steeg, Padma Sheila Rajagopal, Kathleen M. Darcy, Jerry S. H. Lee, Clifton L. Dalgard, Thomas P. Conrads, Emanuel F. Petricoin, Daoud Meerzaman, Matthew D. Wilkerson, APOLLO Research Network, Xiaoying Lin, Craig D. Shriver, Stanley Lipkowitz, Hai Hu
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Online Access:https://doi.org/10.1038/s41523-025-00793-0