The Effect of Natural Health Products and Traditional Medicines on the Activity of Human Hepatic Microsomal-Mediated Metabolism of Oseltamivir

Purpose. Oseltamivir is a prodrug that requires metabolic activation but there is little information on whether natural health products interact to prevent the biotransformation by the carboxylesterase. Methods. HPLC-DAD-ESI-MSD and fluorometric assays were used to determine if 50-pooled mixed gende...

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Bibliographic Details

Published in:	Journal of Pharmacy & Pharmaceutical Sciences
Main Authors:	Rui Liu, Teresa W Tam, Jingqin Mao, Ammar Saleem, Anthony Krantis, John T Arnason, Brian C Foster
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2010-02-01
Online Access:	https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/6808