Regulatory T cells inhibit autoantigen-specific CD4+ T cell responses in lupus-prone NZB/W F1 mice

IntroductionProgressive loss of regulatory T cell (Treg)-mediated control over autoreactive effector T cells contributes to the development of systemic lupus erythematosus (SLE). Accordingly, we hypothesized that Treg may also have the capacity to suppress the activation of autoreactive CD4+ T cells...

詳細記述

書誌詳細

出版年:	Frontiers in Immunology
主要な著者:	Stefan Rosenberger, Reinmar Undeutsch, Reza Akbarzadeh, Justus Ohmes, Philipp Enghard, Gabriela Riemekasten, Jens Y. Humrich
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2023-11-01
主題:	autoantigen-specific T cells immune regulation regulatory T cells lupus autoimmunity
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1254176/full