Preventing olanzapine-induced weight gain using betahistine: a study in a rat model with chronic olanzapine treatment.

Olanzapine is the one of first line antipsychotic drug for schizophrenia and other serious mental illness. However, it is associated with troublesome metabolic side-effects, particularly body weight gain and obesity. The antagonistic affinity to histamine H1 receptors (H1R) of antipsychotic drugs ha...

詳細記述

書誌詳細
出版年:PLoS ONE
主要な著者: Jiamei Lian, Xu-Feng Huang, Nagesh Pai, Chao Deng
フォーマット: 論文
言語:英語
出版事項: Public Library of Science (PLoS) 2014-01-01
オンライン・アクセス:http://europepmc.org/articles/PMC4118967?pdf=render