Multi-omics-informed hydrogel design: modulating IL-6 to reduce endoplasmic reticulum stress in bone regeneration

Post-traumatic bone healing exhibits significant heterogeneity, especially in different injury sites. Notably, bone healing progresses more rapidly in alveolar bone defects compared to the slower repair process observed in femoral bone. Given this physiological phenomenon, understanding site-specifi...

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Bibliographic Details

Published in:	Bioactive Materials
Main Authors:	Jiannan Zhou, Jingtao Dai, Shixian Hu, Cancan Qi, Jiahao Chen, Wentai Zhang, Dorothea Alexander, An Li, Yin Xiao, Ping Li
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2026-02-01
Subjects:	Bone regeneration Multi-omics Endoplasmic reticulum stress Interleukin-6 Hydrogel
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452199X25004104