HOXD1 regulates neural crest cells differentiation and polycerate development in sheep

Abstract The polycerate trait in sheep is a complex phenotype regulated by polygenes. However, the mechanism behind multi-horned traits development and growth remains unclear. In this study, neural crest cells (NCCs) were isolated from mouse embryos, and the HOXD1 (Homeobox D1) gene was overexpresse...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Cheng Zhang, Shuhong Zhang, Huifeng Xu, Guan Wang, Huan Zhang, Tenggang Di, Liming Tian, Menghan Chang, Fengyi Gao, Ming Li, Guangli Yang
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-04-01
Subjects:	Sheep Polycerate trait Neural crest cells HOXD1 gene Chemokine CXC
Online Access:	https://doi.org/10.1038/s41598-025-97865-9