Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging

Summary: Rapid release of neurotransmitters in synchrony with action potentials is considered a key hardwired property of synapses. Here, in glutamatergic synapses formed between induced human neurons, we show that action potential-dependent neurotransmitter release becomes progressively desynchroni...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Burak Uzay, Aiden Houcek, Z. Zack Ma, Christine Konradi, Lisa M. Monteggia, Ege T. Kavalali
Format:	Article
Language:	English
Published:	Elsevier 2023-02-01
Subjects:	CP: Neuroscience
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124723000530