B7H3 Immune Checkpoint Overexpression Is Associated with Decreased Complete Response Rates to Neoadjuvant Therapy in Locally Advanced Rectal Cancer

Background and Objectives: Rectal cancer accounts for approximately one-third of colorectal cancers, with over 340,000 deaths globally in 2022. Despite advancements in treatment, the five-year overall survival for locally advanced rectal cancer (LARC) remains at 74%, with significant morbidity. B7H3...

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Bibliographic Details

Published in:	Diagnostics
Main Authors:	Sebastian Curcean, Raluca Maria Hendea, Rares Buiga, Alexandru Tipcu, Andra Curcean, Catalin Vlad, Zsolt Fekete, Alina-Simona Muntean, Daniela Martin, Alexandru Irimie
Format:	Article
Language:	English
Published:	MDPI AG 2024-09-01
Subjects:	B7H3 locally advanced rectal cancer radiotherapy complete response
Online Access:	https://www.mdpi.com/2075-4418/14/18/2023