Causal association between 1400 metabolites and dilated cardiomyopathy: a bidirectional two-sample Mendelian randomization analysis

BackgroundDilated cardiomyopathy (DCM) is a cardiac disease with a poor prognosis of unclear etiology. Previous studies have shown that metabolism is associated with DCM. This study investigates the causal relationship between 1400 metabolites and DCM using a two-sample Mendelian randomization (MR)...

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Bibliographic Details
Published in:Frontiers in Endocrinology
Main Authors: Xianghui Zeng, Qingfeng Zeng, Xianggui Wang, Kening Li, Jincheng Wu, Jianping Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Subjects:
dilated cardiomyopathy
metabolites
Mendelian randomization
causal analysis
genetic variants
epidemiology
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1423142/full

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https://www.frontiersin.org/articles/10.3389/fendo.2024.1423142/full

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