Modulation of iron metabolism by new chemicals interacting with the iron regulatory system

Despite the vital role of iron and vulnerability of iron metabolism in disease states, it remains largely unknown whether chemicals interacting with cellular proteins are responsible for perturbation of iron metabolism. We previously demonstrated that cisplatin was an inhibitor of the iron regulator...

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Bibliographic Details

Published in:	Redox Biology
Main Authors:	Yoshiaki Tsuji, Jun Ninomiya-Tsuji, Maurice Y.F. Shen, Benjamin R. DiFrancesco
Format:	Article
Language:	English
Published:	Elsevier 2025-02-01
Subjects:	Iron metabolism IRP2 Reactive oxygen species Oxidative stress Ferritin Transferrin receptor
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231724004221