Enriched Differentiation of Human Otic Sensory Progenitor Cells Derived From Induced Pluripotent Stem Cells

Age-related neurosensory deficit of the inner ear is mostly due to a loss of hair cells (HCs). Development of stem cell-based therapy requires a better understanding of factors and signals that drive stem cells into otic sensory progenitor cells (OSPCs) to replace lost HCs. Human induced pluripotent...

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Bibliographic Details

Published in:	Frontiers in Molecular Neuroscience
Main Authors:	Hanae Lahlou, Emmanuel Nivet, Alejandra Lopez-Juarez, Arnaud Fontbonne, Said Assou, Azel Zine
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-12-01
Subjects:	human otic progenitor cells human induced pluripotent cells otic development embryonic hair cells in vitro differentiation transcriptome (RNA-seq)
Online Access:	https://www.frontiersin.org/article/10.3389/fnmol.2018.00452/full