Aminoguanidine Prevents the Oxidative Stress, Inhibiting Elements of Inflammation, Endothelial Activation, Mesenchymal Markers, and Confers a Renoprotective Effect in Renal Ischemia and Reperfusion Injury

Oxidative stress produces macromolecules dysfunction and cellular damage. Renal ischemia-reperfusion injury (IRI) induces oxidative stress, inflammation, epithelium and endothelium damage, and cessation of renal function. The IRI is an inevitable process during kidney transplantation. Preliminary st...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Consuelo Pasten, Mauricio Lozano, Jocelyn Rocco, Flavio Carrión, Cristobal Alvarado, Jéssica Liberona, Luis Michea, Carlos E. Irarrázabal
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Subjects:	aminoguanidine antioxidants oxidative stress ischemia-reperfusion injury renal protection
Online Access:	https://www.mdpi.com/2076-3921/10/11/1724