A surface metal ion-modified 3D-printed Ti-6Al-4V implant with direct and immunoregulatory antibacterial and osteogenic activity

The high concentration of antibacterial metal ions may exhibit unavoidable toxicity to cells and normal tissues. The application of antibacterial metal ions to activate the immune response and induce macrophages to attack and phagocytose bacteria is a new antimicrobial strategy. Herein, 3D-printed T...

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Bibliographic Details

Published in:	Frontiers in Bioengineering and Biotechnology
Main Authors:	Yipeng Wu, Xiangwen Shi, Jianjun Wang, Yang Li, Jiang Wu, Daqi Jia, Yan Bai, Xiaopei Wu, Yongqing Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	metal ion 3D-printed Ti-6Al-4V immunoregulatory antibacterial activity immunoregulatory osteogenic activity bone infection
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2023.1142264/full