Metabolite Signature of Simvastatin Treatment Involves Multiple Metabolic Pathways

Statins inhibit the 3-hydroxy-3-methylglutaryl-CoA reductase enzyme and are the most widely used medication for hypercholesterolemia. Previous studies on the metabolite signature of simvastatin treatment have included only a small number of metabolites. We performed a high-throughput liquid chromato...

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Bibliographic Details
Published in:Metabolites
Main Authors: Lilian Fernandes Silva, Rowmika Ravi, Jagadish Vangipurapu, Markku Laakso
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Subjects:
simvastatin
metabolomics
metabolites
Online Access:https://www.mdpi.com/2218-1989/12/8/753

Internet

https://www.mdpi.com/2218-1989/12/8/753

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