Effects of solamargine in hepatic metastasis of colorectal cancer: induction of ferroptosis and elimination of cancer stem cells

Abstract Background Colorectal cancer (CRC) is a prevalent malignant tumor globally, ranking third in incidence and second in mortality. Metastasis is the main cause of death in patients with CRC. Solanum nigrum L. (SNL), a traditional Chinese medicinal herb endowed with detoxification, blood circul...

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Bibliographic Details
Published in:Chinese Medicine
Main Authors: Shenglan Liu, Junhong Wu, Hao Huang, Bin Hu, Dong Xie, Fuqiang Cao, Jingxuan Li, Caiyao Guo, WeiJie Peng, Yanli Jin, Wei Dai
Format: Article
Language:English
Published: BMC 2025-07-01
Subjects:
Solamargine
Colorectal cancer
Hepatic metastasis
Ferroptosis
Cancer stem cells
Online Access:https://doi.org/10.1186/s13020-025-01171-5

Internet

https://doi.org/10.1186/s13020-025-01171-5

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