Microglia-Derived Small Extracellular Vesicles Reduce Glioma Growth by Modifying Tumor Cell Metabolism and Enhancing Glutamate Clearance through miR-124

Brain homeostasis needs continuous exchange of intercellular information among neurons, glial cells, and immune cells, namely microglial cells. Extracellular vesicles (EVs) are active players of this process. All the cells of the body, including the brain, release at least two subtypes of EVs, the m...

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Bibliographic Details

Published in:	Cells
Main Authors:	Carmela Serpe, Lucia Monaco, Michela Relucenti, Ludovica Iovino, Pietro Familiari, Ferdinando Scavizzi, Marcello Raspa, Giuseppe Familiari, Laura Civiero, Igea D’Agnano, Cristina Limatola, Myriam Catalano
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Subjects:	microglia extracellular vesicles brain tumors glioma neurotoxicity glutamate
Online Access:	https://www.mdpi.com/2073-4409/10/8/2066