Keto-enol tautomerism in the development of new drugs

The presence of isomers is a huge challenge in the development of new medicinal or pharmaceutical agents because the main goal is to obtain the most active compound with high purity and yield. Tautomerism is a phenomenon quite common in biomolecules that also appears in many drugs, and strategies to...

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Bibliographic Details
Published in:Frontiers in Chemical Biology
Main Authors: Ana Paula Araujo de Oliveira, Camila Anchau Wegermann, Ana Maria Da Costa Ferreira
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
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Online Access:https://www.frontiersin.org/articles/10.3389/fchbi.2024.1400642/full