Pathogenic bacteria target NEDD8-conjugated cullins to hijack host-cell signaling pathways.

The cycle inhibiting factors (Cif), produced by pathogenic bacteria isolated from vertebrates and invertebrates, belong to a family of molecules called cyclomodulins that interfere with the eukaryotic cell cycle. Cif blocks the cell cycle at both the G₁/S and G₂/M transitions by inducing the stabili...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	PLoS Pathogens
المؤلفون الرئيسيون:	Grégory Jubelin, Frédéric Taieb, David M Duda, Yun Hsu, Ascel Samba-Louaka, Rika Nobe, Marie Penary, Claude Watrin, Jean-Philippe Nougayrède, Brenda A Schulman, C Erec Stebbins, Eric Oswald
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Public Library of Science (PLoS) 2010-09-01
الوصول للمادة أونلاين:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20941356/pdf/?tool=EBI