JFK Is a Hypoxia-Inducible Gene That Functions to Promote Breast Carcinogenesis

Many carcinomas feature hypoxia, a condition has long been associated with tumor progression and poor prognosis, as well as resistance to chemoradiotherapy. Here, we report that the F-box protein JFK promotes mammary tumor initiation and progression in MMTV-PyMT murine model of spontaneous breast ca...

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書誌詳細

出版年:	Frontiers in Cell and Developmental Biology
主要な著者:	Ziran Yang, Xuehong Zhou, Enrun Zheng, Yizhou Wang, Xinhua Liu, Yue Wang, Yanpu Wang, Zhaofei Liu, Fei Pei, Yue Zhang, Jie Ren, Yunchao Huang, Lu Xia, Sudun Guan, Sen Qin, Feiya Suo, Jie Shi, Lijing Wang, Lin He, Luyang Sun
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2021-07-01
主題:	breast carcinogenesis transcriptional regulation cancer metabolism hypoxia JFK
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fcell.2021.686737/full