Identification of transcription factor binding sites using ATAC-seq

Abstract Transposase-Accessible Chromatin followed by sequencing (ATAC-seq) is a simple protocol for detection of open chromatin. Computational footprinting, the search for regions with depletion of cleavage events due to transcription factor binding, is poorly understood for ATAC-seq. We propose th...

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Bibliographic Details
Published in:Genome Biology
Main Authors: Zhijian Li, Marcel H. Schulz, Thomas Look, Matthias Begemann, Martin Zenke, Ivan G. Costa
Format: Article
Language:English
Published: BMC 2019-02-01
Subjects:
Computational footprinting
Open chromatin
ATAC-seq
Cleavage bias
Online Access:http://link.springer.com/article/10.1186/s13059-019-1642-2

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http://link.springer.com/article/10.1186/s13059-019-1642-2

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