Natural flavonoids act as potent ferroptosis inhibitors and their potentials in the treatment of ferroptosis-associated diseases

Backgrounds: Ferroptosis, an iron-dependent cell death characterized by lethal lipid peroxidation, has been involved in the pathogenesis of various diseases, such as ischemia/reperfusion injury, neurodegenerative diseases, and inflammatory disorders. Pharmacological inhibition of ferroptosis represe...

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Bibliographic Details

Published in:	Pharmacological Research - Modern Chinese Medicine
Main Authors:	Lu Liu, Lun Wang, Ying Xiao, Yue Liu, Xianli Meng, Xiaofei Shen
Format:	Article
Language:	English
Published:	Elsevier 2024-03-01
Subjects:	Ferroptosis Lipid peroxidation Iron metabolism Reactive oxygen species Nrf2 pathway
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667142524000228