Recent Progress on the Localization of the Spindle Assembly Checkpoint Machinery to Kinetochores

Faithful chromosome segregation during mitosis is crucial for maintaining genome stability. The spindle assembly checkpoint (SAC) is a surveillance mechanism that ensures accurate mitotic progression. Defective SAC signaling leads to premature sister chromatid separation and aneuploid daughter cells...

詳細記述

書誌詳細

出版年:	Cells
主要な著者:	Zhen Dou, Diogjena Katerina Prifti, Ping Gui, Xing Liu, Sabine Elowe, Xuebiao Yao
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2019-03-01
主題:	spindle assembly checkpoint (SAC) kinetochore microtubule kinase localization
オンライン･アクセス:	https://www.mdpi.com/2073-4409/8/3/278