A role for phagocytosis in inducing cell death during thymocyte negative selection

Autoreactive thymocytes are eliminated during negative selection in the thymus, a process important for establishing self-tolerance. Thymic phagocytes serve to remove dead thymocytes, but whether they play additional roles during negative selection remains unclear. Here, using a murine thymic slice...

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Bibliographic Details

Published in:	eLife
Main Authors:	Nadia S Kurd, Lydia K Lutes, Jaewon Yoon, Shiao Wei Chan, Ivan L Dzhagalov, Ashley R Hoover, Ellen A Robey
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2019-12-01
Subjects:	central tolerance negative selection thymocyte phagocytosis
Online Access:	https://elifesciences.org/articles/48097