Perindopril sensitizes hepatocellular carcinoma to chemotherapy: A possible role of leptin / Wnt/ β-catenin axis with subsequent inhibition of liver cancer stem cells

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death. The major challenge in managing HCC is the resistance to chemotherapy. Leptin hormone is associated with different oncogenic pathways implicated in drug resistance. Angiotensin II was found to decrease the productio...

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Bibliographic Details

Published in:	Saudi Pharmaceutical Journal
Main Authors:	Sherin Zakaria, Shady Allam, Alaa E. El-Sisi
Format:	Article
Language:	English
Published:	Springer 2022-08-01
Subjects:	Perindopril Leptin Wnt β-catenin ALDH1
Online Access:	http://www.sciencedirect.com/science/article/pii/S1319016422001645