In Silico Study of Correlation between Missense Variations of F8 Gene and Inhibitor Formation in Severe Hemophilia A

Objective: Deleterious substitutions of the F8 gene are responsible for causing hemophilia A, which is an inherited bleeding disorder resulting from reduced or absent activity of the coagulant protein factor VIII (FVIII). The most important complication in treatment is inhibitor development toward t...

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書誌詳細

出版年:	Turkish Journal of Hematology
主要な著者:	Mostefa Fodil, Faouzia Zemani
フォーマット:	論文
言語:	英語
出版事項:	Turkish Society of Hematology 2020-05-01
主題:	hemophilia a missense variation in silico analysis inhibitor formation fviii coagulation
オンライン･アクセス:	https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-09633