Adjuvant role of Ocimum sanctum hydroalcoholic extract with carbamazepine and phenytoin in experimental model of acute seizures

Purpose: This study assessed adjuvant potential of Ocimum sanctum hydroalcoholic extract (OSHE) with antiepileptic drugs (AEDs) carbamazepine (CBZ) and phenytoin (PHT) in maximal electroshock seizure (MES) model in male Wistar rats. Material and Methods: Pharmacodynamic effect of OSHE (1000 mg/kg) w...

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Bibliographic Details

Published in:	Saudi Pharmaceutical Journal
Main Authors:	Sudhir Chandra Sarangi, Soumya Sucharita Pattnaik, Dipesh Joshi, P. Prarthana Chandra, Thomas Kaleekal
Format:	Article
Language:	English
Published:	Springer 2020-11-01
Subjects:	Ocimum sanctum Carbamazepine Phenytoin Maximal electroshock seizure Morris water maze Oxidative stress
Online Access:	http://www.sciencedirect.com/science/article/pii/S1319016420302176