Hibiscetin attenuates oxidative, nitrative stress and neuroinflammation via suppression of TNF-α signaling in rotenone induced parkinsonism in rats

Parkinson's disease (PD) is the gradual and selective degradation of dopamine-releasing neurons in substantia nigra pars compacta (SNpc) and results in postural instability, stiffness, bradykinesia, and resting tremor. The goal of this research was to see how hibiscetin action on PD in rotenone...

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Bibliographic Details

Published in:	Saudi Pharmaceutical Journal
Main Authors:	Sami I. Alzarea, Muhammad Afzal, Khalid Saad Alharbi, Abdulaziz I. Alzarea, Sattam Khulaif Alenezi, Mohammed Salem Alshammari, Ali Alquraini, Imran Kazmi
Format:	Article
Language:	English
Published:	Springer 2022-12-01
Subjects:	Flavonoids Hibiscetin Neurodegeneration Neuroinflammation Neuroprotective
Online Access:	http://www.sciencedirect.com/science/article/pii/S131901642200247X