Construction of a pH-responsive drug delivery platform based on the hybrid of mesoporous silica and chitosan

Mesoporous silica nanoparticles (MSN) have been widely used for drug delivery due to their large specific surface area and excellent biocompatibility. However, the mesoporous structure of MSN would lead to the inevitable “premature release” of the drugs, and therefore the modification of MSN for con...

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Bibliographic Details

Published in:	Journal of Saudi Chemical Society
Main Authors:	Keliang Zhang, Jun Gao, Shangji Li, Ting Ma, Linhong Deng, Yong Kong
Format:	Article
Language:	English
Published:	Springer 2021-01-01
Subjects:	Mesoporous silica Chitosan pH-sensitivity Drug delivery Methotrexate
Online Access:	http://www.sciencedirect.com/science/article/pii/S131961032030154X