Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease

Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease

Glial cells have increasingly been implicated as active participants in the pathogenesis of neurological diseases, but critical pathways and mechanisms controlling glial function and secondary non-cell autonomous neuronal injury remain incompletely defined. Here we use models of Alexander disease, a...

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Bibliographic Details
Main Authors: Wang, Liqun (Author), Xia, Jing (Contributor), Li, Jonathan (Contributor), Hagemann, Tracy L. (Author), Jones, Jeffrey R. (Author), Fraenkel, Ernest (Contributor), Weitz, David A. (Author), Zhang, Su-Chun (Author), Messing, Albee (Author), Feany, Mel B. (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2018-09-05T18:06:06Z.
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