Repurposing Old Drugs into New Epigenetic Inhibitors: Promising Candidates for Cancer Treatment?

by Filipa Moreira-Silva, Vânia Camilo, Vítor Gaspar, João F. Mano, Rui Henrique, Carmen Jerónimo
Published 2020-04-01

Human Germ Cell Tumors are Developmental Cancers: Impact of Epigenetics on Pathobiology and Clinic

by João Lobo, Ad J. M. Gillis, Carmen Jerónimo, Rui Henrique, Leendert H. J. Looijenga
Published 2019-01-01

Downregulation of miR-130b~301b cluster is mediated by aberrant promoter methylation and impairs cellular senescence in prostate cancer

by João Ramalho-Carvalho, Inês Graça, Antonio Gomez, Jorge Oliveira, Rui Henrique, Manel Esteller, Carmen Jerónimo
Published 2017-02-01

Circulating MicroRNAs as Biomarkers for Prostate Cancer Detection and Metastasis Development Prediction

by David Bidarra, David Bidarra, Vera Constâncio, Vera Constâncio, Daniela Barros-Silva, João Ramalho-Carvalho, Catarina Moreira-Barbosa, Luís Antunes, Joaquina Maurício, Jorge Oliveira, Rui Henrique, Rui Henrique, Rui Henrique, Carmen Jerónimo, Carmen Jerónimo
Published 2019-09-01

Practicability of clinical application of bladder cancer molecular classification and additional value of epithelial-to-mesenchymal transition: prognostic value of vimentin express...

by João Lobo, Sara Monteiro-Reis, Catarina Guimarães-Teixeira, Paula Lopes, Isa Carneiro, Carmen Jerónimo, Rui Henrique
Published 2020-08-01

Endometrial Endometrioid Carcinoma Metastases Show Decreased ER-Alpha and PR-A Expression Compared to Matched Primary Tumors.

by Carla Bartosch, Sara Monteiro-Reis, Renata Vieira, Armindo Pereira, Marta Rodrigues, Carmen Jerónimo, José M Lopes
Published 2015-01-01

TMPRSS2-ERG Gene Fusion Causing ERG Overexpression Precedes Chromosome Copy Number Changes in Prostate Carcinomas, Paired HGPIN Lesions

by Nuno Cerveira, Franclim R. Ribeiro, Ana Peixoto, Vera Costa, Rui Henrique, Carmen Jerönimo, Manuel R. Teixeira
Published 2006-10-01

Emerging Lab-on-a-Chip Approaches for Liquid Biopsy in Lung Cancer: Status in CTCs and ctDNA Research and Clinical Validation

by Ângela Carvalho, Gabriela Ferreira, Duarte Seixas, Catarina Guimarães-Teixeira, Rui Henrique, Fernando J. Monteiro, Carmen Jerónimo
Published 2021-04-01

Hydralazine and Panobinostat Attenuate Malignant Properties of Prostate Cancer Cell Lines

by Mariana Brütt Pacheco, Vânia Camilo, Nair Lopes, Filipa Moreira-Silva, Margareta P. Correia, Rui Henrique, Carmen Jerónimo
Published 2021-07-01

Anti-neoplastic and demethylating activity of a newly synthetized flavanone-derived compound in Renal Cell Carcinoma cell lines

by Ângela Marques-Magalhães, Inês Graça, Vera Miranda-Gonçalves, Rui Henrique, Marie Lopez, Paola B. Arimondo, Carmen Jerónimo
Published 2021-09-01

Hydralazine and Enzalutamide: Synergistic Partners against Prostate Cancer

by Nair Lopes, Mariana Brütt Pacheco, Diana Soares-Fernandes, Margareta P. Correia, Vânia Camilo, Rui Henrique, Carmen Jerónimo
Published 2021-08-01

Detailed Characterization of Immune Cell Infiltrate and Expression of Immune Checkpoint Molecules PD-L1/CTLA-4 and MMR Proteins in Testicular Germ Cell Tumors Disclose Novel Diseas...

by João Lobo, Ângelo Rodrigues, Rita Guimarães, Mariana Cantante, Paula Lopes, Joaquina Maurício, Jorge Oliveira, Carmen Jerónimo, Rui Henrique
Published 2019-10-01

Lactate Increases Renal Cell Carcinoma Aggressiveness through Sirtuin 1-Dependent Epithelial Mesenchymal Transition Axis Regulation

by Vera Miranda-Gonçalves, Ana Lameirinhas, Catarina Macedo-Silva, João Lobo, Paula C. Dias, Verónica Ferreira, Rui Henrique, Carmen Jerónimo
Published 2020-04-01

VIRMA-Dependent N6-Methyladenosine Modifications Regulate the Expression of Long Non-Coding RNAs CCAT1 and CCAT2 in Prostate Cancer

by Daniela Barros-Silva, João Lobo, Catarina Guimarães-Teixeira, Isa Carneiro, Jorge Oliveira, Elena S. Martens-Uzunova, Rui Henrique, Carmen Jerónimo
Published 2020-03-01

Overexpression of the Mitotic Checkpoint Genes BUB1 and BUBR1 is Associated with Genomic Complexity in Clear Cell Kidney Carcinomas

by Mafalda Pinto, Joana Vieira, Franclim R. Ribeiro, Maria J. Soares, Rui Henrique, Jorge Oliveira, Carmen Jerónimo, Manuel R. Teixeira
Published 2008-01-01

The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines

by Filipa Quintela Vieira, Ângela Marques-Magalhães, Vera Miranda-Gonçalves, Ricardo Ferraz, Mónica Vieira, Cristina Prudêncio, Carmen Jerónimo, Regina Augusta Silva
Published 2020-12-01

Identification of clear cell renal cell carcinoma and oncocytoma using a three-gene promoter methylation panel

by Ana Sílvia Pires-Luís, Pedro Costa-Pinheiro, Maria João Ferreira, Luís Antunes, Francisco Lobo, Jorge Oliveira, Rui Henrique, Carmen Jerónimo
Published 2017-06-01

Targeting Germ Cell Tumors with the Newly Synthesized Flavanone-Derived Compound MLo1302 Efficiently Reduces Tumor Cell Viability and Induces Apoptosis and Cell Cycle Arrest

by João Lobo, Ana Rita Cardoso, Vera Miranda-Gonçalves, Leendert H. J. Looijenga, Marie Lopez, Paola B. Arimondo, Rui Henrique, Carmen Jerónimo
Published 2021-01-01

A rapid and simple procedure for the establishment of human normal and cancer renal primary cell cultures from surgical specimens.

by Maria João Valente, Rui Henrique, Vera L Costa, Carmen Jerónimo, Félix Carvalho, Maria L Bastos, Paula Guedes de Pinho, Márcia Carvalho
Published 2011-01-01

GC-MS Metabolomics Reveals Distinct Profiles of Low- and High-Grade Bladder Cancer Cultured Cells

by Daniela Rodrigues, Joana Pinto, Ana Margarida Araújo, Carmen Jerónimo, Rui Henrique, Maria de Lourdes Bastos, Paula Guedes de Pinho, Márcia Carvalho
Published 2019-01-01